Web19 aug. 2013 · Die MLSB-Resistenz beruht auf einer Veränderung der Zielstruktur für die Wirkung der genannten Antibiotika. Für Makrolide, Lincosamide und Streptogramin (MLS) ist die Bindung an Adenin 2058 der 23S-rRNA essentiell für die antibiotische Aktivität. Der Resistenzmechanismus besteht darin, dass Methyltransferasen exprimiert werden, die …
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