Immunophilin family
Witryna1 sty 2003 · Each immunophilin family has been structurally characterised with a variety of small molecule ligands, principally immunosuppressive drugs and their … Witryna1 lip 1996 · Immunophilins are members of a highly conserved family of proteins all of which are cis-trans peptidyl-prolyl isomerases. The prototypic members of the …
Immunophilin family
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Witryna21 paź 2008 · The Arabidopsis immunophilin family consists of 29 cyclophilin and 22 FKBP isoforms distributed in various cellular locations ().Perhaps most striking is the …
WitrynaHSP56 is a cis-trans prolyl isomerase belonging to the immunophilin protein family. The human HSP 56 gene (FKBP4) has multiple polyadenylation sites and the HSP 56 protein can undergo phosphorylation. HSP 56 influences immunoregulatory gene expression in lymphocytes, protein folding and trafficking. Witrynadomains [5]. Members of the immunophilin family are ubiquitously expressed, highly conserved proteins which bind immunosuppressant drugs and display peptidyl-prolyl isomerase (PPIase) activity, the latter responsible for their well documented role in protein folding and maturation [6, 7]. Those immunophilins
Witryna26 mar 2004 · Europe PMC is an archive of life sciences journal literature. WitrynaNicholas J Turner. Cyclophilin A (CypA) is a member of the immunophilin family of proteins and receptor for the immunosuppressant drug cyclosporin A (CsA). Here we describe the design and ...
WitrynaFK506-binding proteins (FKBPs) belong to the immunophilin family and bind immunosuppressive drugs, such as FK506 and rapamycin. These proteins, through …
WitrynaCurrent data suggest that FKBP12 functions as a "guardian" for the type I receptors to prevent them from leaky signaling under sub-optimal ligand concentrations, thereby … freak fighters 2WitrynaEach immunophilin family has been structurally characterised with a variety of small molecule ligands, principally immunosuppressive drugs and their analogues and an … freak fighter co to jestWitryna15 cze 2012 · This protein family has been shown to be overexpressed in certain cancers and cancer cell lines. Grb7 and a receptor tyrosine kinase (RTK), erbB2, are … blender not all options shownWitryna31 paź 2013 · Cyclophilin A (CyPA) is a ubiquitously distributed protein belonging to the immunophilin family. CyPA has peptidyl prolyl cis-trans isomerase (PPIase) activity, … freak fightersWitrynaImmunophilin • FK506-binding protein • Peptidylprolyl cis/trans isomerase • Immunophilin ligand • Neuroprotection • FK506 • Rapamycin Abstract Immunophilins … freak fight co toWitrynaFK506-binding proteins (FKBP) belong to the immunophilin family and are best known for their ability to enable the immunosuppressive properties of FK506 and rapamycin. For rapamycin, this is achieved by inducing inhibitory ternary complexes with the kinase mTOR. The essential accessory protein for this gain-of-function was thought to be … blender not allowing edit modeWitryna2 paź 2007 · In Arabidopsis, genes encoding 52 putative immunophilins have been identified: 23 FKBPs and 29 CYPs ().This group is by far the largest immunophilin … blender not chopping ice