WebThe HORRAD trial enrolled 432 patients with de novo metastatic prostate cancer to bone. Patients were randomized to ADT with or without RT to the prostate. For the whole … Web17 mei 2024 · The HORRAD trial was a multicenter, randomized controlled trial of 432 patients with PSA levels of more than 20 ng/mL and bone-predominant metastatic prostate cancer. Patients were randomly assigned (1:1) to external beam RT (70 Gy in 35 fractions or 57.76 Gy in 19 fractions) to the prostate with ADT (RT group) or ADT alone (control group).
Radiotherapy to the primary tumour for newly diagnosed, …
Web10 sep. 2024 · This treatment includes DOC (CHAARTED [Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer] trial supported by STAMPEDE [Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy] Arm C and GETUG-15), AAP (LATITUDE [Abiraterone … Web1 sep. 2024 · Prostate Cancer and Prostatic Diseases ... 2016. Similarly, the North American HORRAD trial also suggested that selected mPCa patients might profit of androgen deprivation therapy ... community cohesion in swimming
Effect on Survival of Androgen Deprivation Therapy Alone Comp…
WebIn the treatment of prostate cancer, radiotherapy has demonstrated clinical benefits in both de novo and metachronous low-volume metastatic disease. Parker et al 8 showed that the addition of prostate radiotherapy to standard systemic treatment improves overall survival for men with de novo metastatic prostate cancer with low metastatic burden. WebSan Francisco, CA USA (UroToday.com) Herein, we report on the first presentation of the HORRAD trial – the first multi-center randomized controlled trial looking at the role of treatment of the primary prostate cancer malignancy in the setting of metastatic disease – to date, no other trials have reported on this clinical disease space. Web19 jun. 2024 · Reacties. Recentelijk werd voor het eerst bewijs geleverd dat met louter een lokale behandeling van een maligne prostaattumor de overleving van patiënten met een beperkt gemetastaseerde ziekte verbeterd kan worden. 1 Dit resultaat kwam van de STAMPEDE-trial en is bijzonder relevant, omdat het ingaat tegen een lang bestaande … community cohort