Golgi reassembly-stacking protein 2
WebThe precise mechanism controlling the Golgi cisternae assembly is not yet known, but it is widely accepted that the Golgi Reassembly and Stacking Protein (GRASP) is a main … WebGolgi reassembly-stacking protein of 55 k Da (GRASP55) also known as golgi reassembly-stacking protein 2 (GORASP2) is a protein that in humans is encoded by the GORASP2 gene. It was identified by its homology with GRASP65 and the protein's amino acid sequence was determined by analysis of a molecular clone of its complementary …
Golgi reassembly-stacking protein 2
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WebGolgi reassembly-stacking protein 2, golgi reassembly-stacking protein of 55 kDa GeneRIFs: Gene References Into Functions The function of GORASPs in Golgi apparatus organization in vivo. GRASP55 Is Dispensable for Normal Hematopoiesis but Necessary for Myc-Dependent Leukemic Growth. WebAbstract. Two classes of proteins that bind to each other and to Golgi membranes have been implicated in the adhesion of Golgi cisternae to each other to form their characteristic stacks: Golgi reassembly and stacking proteins 55 and 65 (GRASP55 and GRASP65) and Golgin of 45 kDa and Golgi matrix protein of 130 kDa.
WebNov 26, 2024 · Golgi reassembly and stacking protein 65 (GRASP65), which has been involved in cancer progression, is associated with tumor growth and cell apoptosis. Dihydromyricetin (DHM) has demonstrated antitumor activity in different types of human cancers. However, the pharmacological effects of DHM on ovaria … WebNov 1, 2024 · Here, we show that SIRT2 depletion causes Golgi fragmentation and impairs Golgi reassembly at the end of mitosis. SIRT2 interacts with the Golgi reassembly stacking protein GRASP55 (also known as GORASP2) in mitosis when GRASP55 is highly acetylated on K50. Expression of wild-type and the K50R acetylation-deficient mutant of …
WebDespite lacking a signal peptide, assays in vitro by western blot and in vivo by confocal microscopy revealed that secretion of VdSOD1 is dependent on the Golgi reassembly stacking protein (VdGRASP). Both menadione-treated ΔSOD1 and cotton roots infected with ΔSOD1 accumulated more O 2-and less H 2 O 2 than with the wildtype strain. The ... WebFeb 15, 2024 · Abstract In mammalian cells, the Golgi reassembly stacking protein of 65 kDa (GRASP65) has been implicated in both Golgi stacking and ribbon linking by forming trans-oligomers. To better understand its function and regulation, we used biochemical methods to identify the DnaJ homolog subfamily A member 1 (DjA1) as a novel …
WebJan 4, 2024 · The authors uncovered miR-34a as a regulator of a conventional protein secretion axis, which is mediated by three proteins: the Golgi reassembly and stacking protein 55 kDa (GRASP55), basic leucine zipper nuclear factor 1, and myosin IIA.
WebJan 6, 2016 · The Golgi apparatus is a central intracellular membrane organelle for trafficking and modification of proteins and lipids. Its basic structure is a stack of tightly aligned flat cisternae. In mammalian cells, dozens of stacks are concentrated in the pericentriolar region and laterally connected to form a ribbon. richmondcc owschoolsWebGolgi reassembly stacking protein 2. Gene Name. GORASP2. Alternative Gene Names. GOLPH6, GRASP55, GRS2. UniProt ID. Q9H8Y8. Gene (Ensembl) ENSG00000115806. Entrez Gene ID. Entrez gene: 26003. … richmond cbs tvWebProtein target information for Golgi reassembly stacking protein 2 (dog). Find diseases associated with this biological target and compounds tested against it in bioassay … red river ex light show 2021WebJan 23, 2007 · Protein Golgi reassembly-stacking protein 1 Gene GORASP1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 440 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Download Add a publication Entry … richmond cboc addressWebJan 23, 2007 · Golgi reassembly-stacking protein 2 Short names GRS2 Alternative names Golgi phosphoprotein 6 ( GOLPH6) Golgi reassembly-stacking protein of 55 … red river ex winter wonderlandWebTerm: Qualifier: Evidence: With: Reference: Notes: Source: Original Reference(s) 1,2-dimethylhydrazine : increases expression: ISO: RGD:731767: 6480464: 1, 2 ... richmond ccg contact numberWebNov 26, 2024 · Golgi reassembly and stacking protein 65 (GRASP65), which has been involved in cancer progression, is associated with tumor growth and cell apoptosis. Dihydromyricetin (DHM) has demonstrated antitumor activity in different types of human cancers. However, the pharmacological effects of DHM on ovarian cancer (OC) and the … red river ex tickets 2022