WebNov 29, 2024 · Dapsone is an antibacterial medicine. It is prescribed for the treatment of two completely different conditions - a disease called leprosy, and a skin condition called dermatitis herpetiformis. It is also prescribed for people with a weakened immune system to protect them from pneumonia caused by an infection with germs (bacteria) called ... WebThe elimination half-life of dapsone is about 30 hours. The drug shows linear pharmacokinetics within the therapeutic range and the time-course after oral administration fits a 2-compartment model. The concentration-time profile of dapsone after parenteral administration is reviewed. Of clinical importance is the development of a new long ...
Dapsone Article - StatPearls
WebThe metabolism of dapsone is mediated by CYP3A4, coadministration of drugs that inhibit CYP3A4, such as saquinavir boosted with ritonavir, may cause decreased clearance of dapsone. Simeprevir: (Minor) Simeprevir, a mild intestinal CYP3A4 inhibitor, may increase the side effects of dapsone, which is a CYP3A4 substrate. WebJun 4, 2015 · Dapsone is a standard second-line treatment of primary immune thrombocytopenia (ITP), with response rates of 27% to 63%. Most adult studies used 100 mg daily, but the rationale for dose selection is unclear, and no ITP study has sought an association between dose and response. Dapsone’s mechanism of action in ITP is not … promotional custom rattles
Clinical pharmacokinetics of dapsone - PubMed
WebDapsone is used to treat various skin conditions including: Dermatitis herpetiformis Linear IgA bullous dermatosis Vasculitis Pyoderma gangrenosum Sweet disease Aphthous … WebNov 9, 2024 · Dapsone is an anti-infective medicine that fights bacteria. Dapsone is used to treat dermatitis herpetiformis (a skin condition) and leprosy. Dapsone may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your … These classifications are only a guideline. The relevance of a particular drug … Generic name: Dapsone (systemic) [ DAP-sone ] Drug class: Leprostatics … Subscribe to Drugs.com newsletters for the latest medication news, new drug … Drug Levels. Maternal Levels. In one mother who was 41 days postpartum, a … Dapsone is excreted into human milk. Hemolytic reactions have been reported … Subscribe to Drugs.com newsletters for the latest medication news, new drug … WebFeb 17, 2024 · Diabetes mellitus: Dapsone may artificially lower HbA 1C by reducing erythrocyte survival time through hemolysis (Lai 2012). Concurrent drug therapy issues: Drug-drug interactions: Potentially significant interactions may exist, requiring dose or frequency adjustment, additional monitoring, and/or selection of alternative therapy. labs and kidney failure