Bsp bone
WebBone sialoprotein (BSP) is an acidic, phosphorylated glycoprotein that is synthesized by osteoblasts and osteoclastic-like cells in culture. It has an unglycosylated mass of 33 kDa (glycosylated, 70–80 kDa). Although the function of BSP is still not fully understood, BSP stimulates hydroxyapatite formation in vitro and appears to mediate cell ... Web2. Bone sialoprotein. Human bone sialoprotein (BSP), a 33 kDa glycoprotein, is a major non-collagenous extracellular protein of mineralized tissues such as bone, dentin, cementum, and calcified cartilage [].BSP has an apparent molecular weight of 60–80 kDa due to extensive post-translational modifications including N-and O-linked glycosylation, …
Bsp bone
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WebInterleukin-6 (IL-6)-type cytokines are pleiotropic molecules capable of stimulating bone resorption and expressed by numerous cell types. In the present study, we tested the hypothesis that gingival fibroblasts may exert local osteotropic effects through production of IL-6 and related cytokines. WebBone Sialoprotein Structure of Growth Plate and Bone Matrix. Bone sialoprotein is the second major sialoprotein of bone [2 ]. It is also... Biochemical Dynamics. MARKUS J. …
WebFeb 24, 2015 · Bone sialoprotein (BSP) belongs to the "small integrin-binding ligand N-linked glycoprotein" (SIBLING) family, whose members interact with bone cells and bone mineral. BSP is strongly expressed in … WebJan 8, 2024 · YAP and TAZ function in bone: conflicting evidence. Roles for YAP and TAZ in osteogenesis were first described in 2004 and 2005, respectively (23, 24).YAP was reported to suppress osteoblastic differentiation through sequestration and transcriptional repression of Runx2 (), whereas TAZ was identified as a Runx2 coactivator and an …
WebBSP protein expression in the primary resected non-small-cell lung cancer is strongly associated with bone metastasis and could be used to identify high-risk patients. cooperative mechanisms by which BSP can enhance specific factors associated with a metastatic phenotype in tumor cell lines, an effect that is increased by circulating TGF … WebThe ability of bone-marrow-derived mesenchymal stem/stromal cells (BM-MSCs) to differentiate into osteoblasts makes them the ideal candidate for cell-based therapies targeting bone-diseases. Polyphosphate (polyP) is increasingly being studied as a potential inorganic source of phosphate for extracellular matrix mineralisation. The aim of this …
WebBone sialoprotein (BSP) is a major protein of the mineralized bone extracellular matrix that has been implicated in the nucleation of hydroxyapatite crystals. Our previous studies have demonstrated that BSP mRNA is expressed by differentiated osteoblasts, odontoblasts, and cementoblasts involved in de novo mineralized tissue formation in a ...
WebMar 3, 2024 · Bone is mostly composed of hydroxyapatite crystals and several types of extracellular matrix proteins, including COL1A1, osteocalcin, osteonectin, secreted phosphoprotein 1 (SPP1), Integrin-Binding Sialoprotein (IBSP) and proteoglycans. Most of these bone matrix proteins are secreted and deposited by polarized mature OBs . The … csi etabs supportWebSep 13, 2012 · IBSP, or bone sialoprotein (BSP), is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and … marchglen alloaWebBSP is a marker of bone metabolism, which can activate osteoblasts, dental osteocyte, or osteoblast like cells, and promote the differentiation of cells into osteoblasts, thus leading to bone mineralization. 31,32 Due to the high expression of BSP in differentiated and mature osteoblasts, BSP can be used as a late marker of osteogenic ... csiet certificationWebThe BSP regularly receive questions and queries from professional colleagues in relation to various aspects of periodontics and periodontal management. We hope to post … march gel nail colorsWebBSP is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms. BSP - What does BSP stand for? The Free Dictionary. ... BSP: Bone Sialoprotein (mineralized tissues) BSP: Bahujan Samaj Party (India) BSP: Bangko Sentral Ng Pilipinas (Central Bank of the Philippines) BSP: csi etab torrentWebFeb 5, 2024 · Bone homeostasis is proverbial for being essentially directed by Wnt-mediated signals . By binding to low-density lipoprotein receptor-related protein 5/6 (LRP5/6), this cascade can be blocked by antagonists such as Dickkopf-1 (DKK-1) [ 52 ]. β-catenin/Wnt pathway can inhibit DPSCs differentiation [ 53 ]. march gladness clipartWebBSP: [ brōm-sul´fah-lēn ] trademark for a preparation of sulfobromophthalein sodium, a dye used in a liver function test called the sulfobromophthalein test . march gnome clip art