Bnf thiazide like diuretic
WebDiuretics — ACE inhibitors can cause a very rapid fall in blood pressure in a person who is volume-depleted. Treatment should be initiated at very low doses. If the dose of diuretic is greater than 80 mg furosemide or equivalent, the ACE inhibitor should be initiated under close supervision and in some cases the diuretic dose may need to be ... WebLike other thiazides, chlorothiazide promotes water loss from the body (diuretics). It inhibits Na + /Cl - reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid.
Bnf thiazide like diuretic
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WebThe effects of a thiazide or thiazide-like diuretic on BP can be divided into three sequential phases: 1) short-term, 2) long-term, and 3) chronic. 73 In the short-term phase, the first 2 to 4 weeks, reductions in BP are related to decreases in cardiac output and plasma volume. At this time, there is an increase in plasma renin activity and a ... WebIndapamide is a thiazide-like diuretic drug used in the treatment of hypertension, as well as decompensated heart failure. Combination preparations with perindopril (an ACE …
WebMar 7, 2011 · Chlorthalidone has a much longer half-life than HCTZ (45 to 60 versus 8 to 15 hours), as well as a much longer duration of action, and, on a per-milligram basis, chlorthalidone is 1.5 to 2.0 times more potent than HCTZ. 5 These 2 observations alone make chlorthalidone putatively a more desirable diuretic than HCTZ for hypertension … WebNational Center for Biotechnology Information
WebThiazide-like diuretic. A thiazide-like diuretic is a sulfonamide diuretic that has similar physiological properties to a thiazide diuretic, but does not have the chemical properties of a thiazide, lacking the benzothiadiazine molecular structure. Examples include metolazone, chlorthalidone, and indapamide. [1] WebThiazides and related diuretics Thiazides and related compounds are moderately potent diuretics; they inhibit sodium reabsorption at the beginning of the distal convoluted tubule. They are usually administered early in the day so …
WebThiazide is a type of drug called a diuretic. It prevents the body from reabsorbing sodium (salt) from the kidneys. Thiazide and diuretics like it are mostly used to treat high blood …
WebThiazide diuretics are a type of diuretic (a drug that increases urine flow). They act directly on the kidneys and promote diuresis (urine flow) by inhibiting the sodium/chloride … harvard iop youth pollWebSummary. Thiazide and thiazide-like diuretics are a class of medications used to treat hypertension and edema by promoting the elimination of salt and water from the body. Thiazide diuretics work by inhibiting … harvard iop youtubeWebChronic heart failure is initially treated with a loop diuretic, usually furosemide supplemented with spironolactone, amiloride hydrochloride, or potassium chloride. If … harvard io psychologyWebHowever, when thiazides, or indeed thiazide-like diuretics such as metolazone, are used in combination with loop diuretics, they facilitate sequential nephron blockade and are … harvard ips coreharvard ip policyWebDavid C. McMillan, in Reference Module in Biomedical Sciences, 2024 Targets-Pharmacodynamics. The primary target of hydrochlorothiazide (and other thiazide/ thiazide-like diuretics) is the sodium-chloride symporter (SLC12A3, NCC) on the apical membrane of the renal distal tubule.Hydrochlorothiazide is transported from the blood to … harvard iran oral historyWebThiazide-like diuretics; Calcium-channel blockers; Spironolactone; Beta-blockers; Alpha-blockers; COVID-19; ... Diuretics — prior treatment with high dose diuretics may result in volume depletion and a risk of hypotension. ... This recommendation for the first dose does not feature in the British National Formulary (BNF) or the information ... harvard iq music test